Reaction Details  Report a problem with these data
Cell Reactant:
Flavin reductase (NADPH)
Syringe Reactant:
BDBM614150
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
10/06/23
ΔG°:
-8.01±0.1 (kcal/mole)
Log10Kb:
-?
Temperature:
298.15±0 (K)
ΔH° :
-3.88±0.07 (kJ/mole)
ΔS° :
0.01±0 (kJ/mole-K)
Citation
 Ryu, K; Kim, M; Griesinger, C; Lee, D Method of increasing platelet counts of a subject US Patent  US11744839 Publication Date 9/5/2023 
Cell React
Name:
Flavin reductase (NADPH)
Synonyms:
1.3.1.24 | 1.5.1.30 | BLVRB | BLVRB_HUMAN | BVR-B | Biliverdin reductase B | Biliverdin-IX beta-reductase | FLR
Type:
PROTEIN
Mol. Mass.:
22123.63
Organism:
Human
Description:
ChEMBL_100283
Residue:
206
Sequence:
MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ
  
Syringe React
Name:
BDBM614150
Synonyms:
US11744839, Compound Phloxine B
Type:
Small organic molecule
Emp. Form.:
C20H2Br4Cl4O5
Mol. Mass.:
783.656
SMILES:
[O-]c1c(Br)cc2c(Oc3c(Br)c([O-])c(Br)cc3C22OC(=O)c3c2c(Cl)c(Cl)c(Cl)c3Cl)c1Br
Structure:
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