Reaction Details  Report a problem with these data
Cell Reactant:
Flavin reductase (NADPH)
Syringe Reactant:
BDBM50582214
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
10/06/23
ΔG°:
-9.14±0.07 (kcal/mole)
Temperature:
298.15±0 (K)
ΔH° :
-10.98±0.07 (kJ/mole)
ΔS° :
-0.01±0 (kJ/mole-K)
Citation
 Ryu, K; Kim, M; Griesinger, C; Lee, D Method of increasing platelet counts of a subject US Patent  US11744839 Publication Date 9/5/2023 
Cell React
Name:
Flavin reductase (NADPH)
Synonyms:
1.3.1.24 | 1.5.1.30 | BLVRB | BLVRB_HUMAN | BVR-B | Biliverdin reductase B | Biliverdin-IX beta-reductase | FLR
Type:
PROTEIN
Mol. Mass.:
22123.63
Organism:
Human
Description:
ChEMBL_100283
Residue:
206
Sequence:
MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ
  
Syringe React
Name:
BDBM50582214
Synonyms:
ATALUREN | Ataluren | PTC-124 | PTC124 | Translarna | US11744839, Compound of formula 4
Type:
Small organic molecule
Emp. Form.:
C15H9FN2O3
Mol. Mass.:
284.242
SMILES:
OC(=O)c1cccc(c1)-c1noc(n1)-c1ccccc1F
Structure:
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