Reaction Details Report a problem with these data
Cell Reactant:
Trypsin
Syringe Reactant:
BDBM775
Meas. Tech.:
Isothermal Titration Calorimetry
Entry Date.:
06/15/04
ΔG°:
-6.15±0.05 (kcal/mole)
pH:
8±n/a
Log10Kb:
3.3
Temperature:
298.35±n/a (K)
ΔH° :
-3.04±0.12 (kJ/mole)
ΔHobs :
-3.04±0.12 (kJ/mole)
Corrected for ΔHioniz:
not known
ΔS° :
0.01±0 (kJ/mole-K)
Citation
Talhout, R; Villa, A; Mark, AE; Engberts, JB Understanding binding affinity: a combined isothermal titration calorimetry/molecular dynamics study of the binding of a series of hydrophobically modified benzamidinium chloride inhibitors to trypsin. J Am Chem Soc 125:10570-9 (2003) [PubMed] Article
Cell React
Source:
no
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bovine
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN