Cell Reactant:
Cyclin-dependent kinase 2
Syringe Reactant:
BDBM225320
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
05/10/17
ΔG°:
-9.14±1.79 (kcal/mole)
Temperature:
298±0 (K)
ΔH° :
-7.25±1.79 (kJ/mole)
ΔS° :
0.01±0 (kJ/mole-K)
Citation
 D3R, DD CSAR CDK2-CyclinA D3R 219:0 (2015) [PubMed] 
Cell React
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Syringe React
Name:
BDBM225320
Synonyms:
CS246
Type:
Small Organic Molecule
Emp. Form.:
C18H13N4O4S2
Mol. Mass.:
413.451
SMILES:
CC(=O)N=S([O-])(=O)c1ccc(N\C=C2/C(=O)Nc3ccc4ncsc4c23)cc1
Structure:
Search PDB for entries with ligand similarity: