Cell Reactant:
Cyclin-dependent kinase 2
Syringe Reactant:
BDBM225311
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
05/10/17
ΔG°:
-8.32±n/a (kcal/mole)
Temperature:
298±0 (K)
ΔH° :
-17.73±0.53 (kJ/mole)
ΔS° :
-0.03±0 (kJ/mole-K)
Citation
 D3R, DD CSAR CDK2 Kinase D3R 220:0 (2015) [PubMed] 
Cell React
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Syringe React
Name:
BDBM225311
Synonyms:
CS3
Type:
Small Organic Molecule
Emp. Form.:
C14H14N4O2
Mol. Mass.:
270.2866
SMILES:
NC(=O)c1ccc(cc1)C(=O)Nc1cc([nH]n1)C1CC1
Structure:
Search PDB for entries with ligand similarity: