Reaction Details Report a problem with these data
Target
E3 ubiquitin-protein ligase XIAP [163-230]/[26-93]
Ligand
BDBM518381
Substrate
n/a
Meas. Tech.
Biological Assay
Ki
<25000±n/a nM
Citation
Cosford, ND; Vamos, MD Inhibitor of apoptosis protein (IAP) antagonists US Patent US11111270 Publication Date 9/7/2021
More Info.:
Target
Name:
E3 ubiquitin-protein ligase XIAP [163-230]/[26-93]
Synonyms:
E3 ubiquitin-protein ligase XIAP BIR1/2
Type:
Protein
Mol. Mass.:
n/a
Description:
n/a
Components:
This complex has 2 components.
Component 1
Name:
E3 ubiquitin-protein ligase XIAP [26-93]
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP/BIR 1 | IAP3 | XIAP | XIAP_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
7519.37
Organism:
Human
Description:
P98170[26-93]
Residue:
68
Sequence:
EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFI
Component 2
Name:
E3 ubiquitin-protein ligase XIAP [163-230]
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP/ BIR2 | IAP3 | XIAP | XIAP_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
7983.41
Organism:
Human
Description:
P98170[163-230]
Residue:
68
Sequence:
EEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFV