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Target
Tyrosine-protein phosphatase non-receptor type 1 [1-405]
Ligand
BDBM604153
Substrate
n/a
Meas. Tech.
Metabolic Measurements
Ki
2000±n/a nM
Citation
 Tonks, N; Krishnan, N Treatment of Rett syndrome US Patent  US11660306 Publication Date 5/30/2023 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 1 [1-405]
Synonyms:
PTN1_HUMAN | PTP1B | PTPN1
Type:
n/a
Mol. Mass.:
46535.71
Organism:
Homo sapiens (Human)
Description:
P18031[1-405]
Residue:
405
Sequence:
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSY
  
Inhibitor
Name:
BDBM604153
Synonyms:
US11660306, Example Friedelin
Type:
Small organic molecule
Emp. Form.:
C30H46O
Mol. Mass.:
422.6856
SMILES:
C[C@H]1C(=O)CC[C@H]2[C@]1(C)CC[C@]13C[C@@]11CC[C@@]4(C)CCC(C)(C)C[C@]44C[C@@]14CC[C@@]23C |r|
Structure:
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