Reaction Details Report a problem with these data
Target
Interleukin-17F
Ligand
BDBM617587
Substrate
n/a
Meas. Tech.
AlphaLISA Assay
IC50
63.1±n/a nM
Citation
 MARTIN, BP; WESTERMANN, J; KERN, OT; HOLMES, AJ; MORRISON, A; KICZUN, M; AL MASRI, M; SMITH, A; HUXLEY, A IL-17A MODULATORS US Patent  US20230286943 Publication Date 9/14/2023 
Target
Name:
Interleukin-17F
Synonyms:
Cytokine ML-1 | IL17F | IL17F_HUMAN | il-17f
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18053.35
Organism:
Homo sapiens (Human)
Description:
Q96PD4
Residue:
163
Sequence:
MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
  
Inhibitor
Name:
BDBM617587
Synonyms:
US20230286943, Example 55
Type:
Small organic molecule
Emp. Form.:
C24H30N6O3
Mol. Mass.:
450.5334
SMILES:
Cc1cnn(C)c1-c1ccc(NC(=O)[C@@H](NC(=O)c2conc2C)C2CCCCCC2)nc1 |r|
Structure:
Search PDB for entries with ligand similarity: