Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM334294
Substrate
n/a
Meas. Tech.
In Vitro Assay
EC50
2145±n/a nM
Citation
 Macielag, MJ; Zhang, Y; DeCorte, BL; Greco, MN; Ludovici, DW; Parker, MH Cinnoline derivatives useful as CB-1 receptor inverse agonists US Patent  US9732061 Publication Date 8/15/2017 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM334294
Synonyms:
US9732061, Compound 16
Type:
Small organic molecule
Emp. Form.:
C31H26Cl2N4O4S2
Mol. Mass.:
653.599
SMILES:
OC(=O)c1ccc(s1)S(=O)(=O)N1CCC(CC1)Nc1cnnc2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1
Structure:
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