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Target
P2Y purinoceptor 1
Ligand
BDBM260858
Substrate
n/a
Meas. Tech.
Scintillation Proximity Assay (SPA)
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
6.70±n/a nM
Comments
extracted
Citation
 LHeureux, A 7-hydroxy-indolinyl antagonists of P2Y1 receptor US Patent  US9540323 Publication Date 1/10/2017 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM260858
Synonyms:
US9540323, 45 | US9540323, example 45
Type:
Small organic molecule
Emp. Form.:
C36H45N5O2
Mol. Mass.:
579.7748
SMILES:
CCC1(CC)CN(c2c1c(ccc2O)C#N)c1ccccc1NC(=O)Nc1ccc(cc1)C1CCN(CC(C)(C)C)CC1
Structure:
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