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Target
Mevalonate kinase
Ligand
BDBM37977
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
72901.5±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM37977
Synonyms:
2-(1-azepanyl)-N-(4-methyl-2-thiazolyl)acetamide;oxalic acid | 2-(azepan-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide;oxalic acid | 2-(azepan-1-yl)-N-(4-methyl-1,3-thiazol-2-yl)ethanamide;ethanedioic acid | 2-(azepan-1-yl)-N-(4-methylthiazol-2-yl)acetamide;oxalic acid | 2-Azepan-1-yl-N-(4-methyl-thiazol-2-yl)-acetamide | MLS000074902 | SMR000008324 | cid_648882
Type:
Small organic molecule
Emp. Form.:
C12H19N3OS
Mol. Mass.:
253.364
SMILES:
Cc1csc(NC(=O)CN2CCCCCC2)n1
Structure:
Search PDB for entries with ligand similarity: