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Target
Mevalonate kinase
Ligand
BDBM38528
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
91181.5±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38528
Synonyms:
2-(4-cyclohexyl-1-piperazinyl)-N-(2-phenylphenyl)acetamide;hydrochloride | 2-(4-cyclohexylpiperazin-1-yl)-N-(2-phenylphenyl)acetamide;hydrochloride | 2-(4-cyclohexylpiperazin-1-yl)-N-(2-phenylphenyl)ethanamide;hydrochloride | 2-(4-cyclohexylpiperazino)-N-(2-phenylphenyl)acetamide;hydrochloride | MLS000030142 | N-Biphenyl-2-yl-2-(4-cyclohexyl-piperazin-1-yl)-acetamide | SMR000008383 | cid_6603387
Type:
Small organic molecule
Emp. Form.:
C24H31N3O
Mol. Mass.:
377.5224
SMILES:
O=C(CN1CCN(CC1)C1CCCCC1)Nc1ccccc1-c1ccccc1
Structure:
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