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Target
Mevalonate kinase
Ligand
BDBM38589
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
69145.8±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38589
Synonyms:
5-(4-methylphenyl)-2H-[1,3]thiazolo[2,3-c][1,2,4]triazole-3-thione | 5-(4-methylphenyl)-2H-thiazolo[2,3-c][1,2,4]triazole-3-thione | 5-(p-tolyl)-2H-thiazolo[2,3-c][1,2,4]triazole-3-thione | MLS000056923 | SMR000066274 | cid_2383729
Type:
Small organic molecule
Emp. Form.:
C11H9N3S2
Mol. Mass.:
247.339
SMILES:
Cc1ccc(cc1)-c1csc2n[nH]c(=S)n12
Structure:
Search PDB for entries with ligand similarity: