Reaction Details Report a problem with these data
Target
Mevalonate kinase
Ligand
BDBM38590
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
100430.4±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38590
Synonyms:
2-[3-(3,5-dimethyl-1-pyrazolyl)propylamino]-1-phenylethanol;oxalic acid | 2-[3-(3,5-dimethylpyrazol-1-yl)propylamino]-1-phenyl-ethanol;ethanedioic acid | 2-[3-(3,5-dimethylpyrazol-1-yl)propylamino]-1-phenyl-ethanol;oxalic acid | 2-[3-(3,5-dimethylpyrazol-1-yl)propylamino]-1-phenylethanol;oxalic acid | MLS000058314 | SMR000063505 | cid_2999794
Type:
Small organic molecule
Emp. Form.:
C16H23N3O
Mol. Mass.:
273.3733
SMILES:
Cc1cc(C)n(CCCNCC(O)c2ccccc2)n1
Structure:
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