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Target
14-3-3 protein gamma
Ligand
BDBM39861
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39861
Synonyms:
Cyclopropanecarboxylic acid [1,4]dioxan-2-ylmethyl-(6-ethoxy-2-oxo-1,2-dihydro-quinolin-3-ylmethyl)-amide | MLS000031787 | N-(1,4-dioxan-2-ylmethyl)-N-[(6-ethoxy-2-keto-1H-quinolin-3-yl)methyl]cyclopropanecarboxamide | N-(1,4-dioxan-2-ylmethyl)-N-[(6-ethoxy-2-oxidanylidene-1H-quinolin-3-yl)methyl]cyclopropanecarboxamide | N-(1,4-dioxan-2-ylmethyl)-N-[(6-ethoxy-2-oxo-1H-quinolin-3-yl)methyl]cyclopropanecarboxamide | SMR000005826 | cid_655565
Type:
Small organic molecule
Emp. Form.:
C21H26N2O5
Mol. Mass.:
386.4415
SMILES:
CCOc1ccc2[nH]c(=O)c(CN(CC3COCCO3)C(=O)C3CC3)cc2c1
Structure:
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