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Target
Cathepsin B
Ligand
BDBM37147
Substrate
n/a
Meas. Tech.
Cathepsin B dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM37147
Synonyms:
4-[5-[(5-methyl-2-propan-2-yl-phenoxy)methyl]-1,2,4-oxadiazol-3-yl]-1,2,5-oxadiazol-3-amine | 4-[5-[(5-methyl-2-propan-2-ylphenoxy)methyl]-1,2,4-oxadiazol-3-yl]-1,2,5-oxadiazol-3-amine | MLS000119200 | SMR000096128 | [4-[5-[(2-isopropyl-5-methyl-phenoxy)methyl]-1,2,4-oxadiazol-3-yl]furazan-3-yl]amine | cid_715594
Type:
Small organic molecule
Emp. Form.:
C15H17N5O3
Mol. Mass.:
315.3272
SMILES:
CC(C)c1ccc(C)cc1OCc1nc(no1)-c1nonc1N
Structure:
Search PDB for entries with ligand similarity: