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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42137
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42137
Synonyms:
4-[[2-methoxy-5-(1-propan-2-yl-5-tetrazolyl)phenyl]sulfonylamino]benzoic acid ethyl ester | 4-[[5-(1-isopropyltetrazol-5-yl)-2-methoxy-phenyl]sulfonylamino]benzoic acid ethyl ester | MLS000078513 | SMR000041225 | cid_660389 | ethyl 4-[[2-methoxy-5-(1-propan-2-yl-1,2,3,4-tetrazol-5-yl)phenyl]sulfonylamino]benzoate | ethyl 4-[[2-methoxy-5-(1-propan-2-yltetrazol-5-yl)phenyl]sulfonylamino]benzoate
Type:
Small organic molecule
Emp. Form.:
C20H23N5O5S
Mol. Mass.:
445.492
SMILES:
CCOC(=O)c1ccc(NS(=O)(=O)c2cc(ccc2OC)-c2nnnn2C(C)C)cc1
Structure:
Search PDB for entries with ligand similarity: