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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM30834
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM30834
Synonyms:
6-amino-1-benzyl-5-[(2-fluorobenzyl)amino]pyrimidine-2,4-quinone | 6-amino-1-benzyl-5-[(2-fluorophenyl)methylamino]pyrimidine-2,4-dione | 6-amino-5-[(2-fluorophenyl)methylamino]-1-(phenylmethyl)pyrimidine-2,4-dione | 6-azanyl-5-[(2-fluorophenyl)methylamino]-1-(phenylmethyl)pyrimidine-2,4-dione | MLS000098252 | SMR000066930 | cid_2116196
Type:
Small organic molecule
Emp. Form.:
C18H17FN4O2
Mol. Mass.:
340.3516
SMILES:
Nc1c(NCc2ccccc2F)c(=O)[nH]c(=O)n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: