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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42148
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42148
Synonyms:
(4Z)-2-methyl-5-oxo-4-[(2-pyridinylmethylamino)methylidene]-3-benzo[g]benzofurancarboxylic acid ethyl ester | (4Z)-5-keto-2-methyl-4-[(2-pyridylmethylamino)methylene]benzo[g]benzofuran-3-carboxylic acid ethyl ester | MLS000090131 | SMR000024749 | cid_5451737 | ethyl (4Z)-2-methyl-5-oxidanylidene-4-[(pyridin-2-ylmethylamino)methylidene]benzo[g][1]benzofuran-3-carboxylate | ethyl (4Z)-2-methyl-5-oxo-4-[(pyridin-2-ylmethylamino)methylidene]benzo[g][1]benzofuran-3-carboxylate | ethyl (4Z)-2-methyl-5-oxo-4-{[(pyridin-2-ylmethyl)amino]methylene}-4,5-dihydronaphtho[1,2-b]furan-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C23H20N2O4
Mol. Mass.:
388.4159
SMILES:
CCOC(=O)c1c(C)oc2c1c(C=NCc1ccccn1)c(O)c1ccccc21 |w:13.14|
Structure:
Search PDB for entries with ligand similarity: