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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42157
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42157
Synonyms:
4-[2-(1-keto-3-methyl-2-isoquinolyl)acetyl]piperazine-1-carboxylic acid ethyl ester | 4-[2-(3-methyl-1-oxo-2-isoquinolinyl)-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester | MLS000086253 | SMR000021762 | cid_3243634 | ethyl 4-[(3-methyl-1-oxoisoquinolin-2(1H)-yl)acetyl]piperazine-1-carboxylate | ethyl 4-[2-(3-methyl-1-oxidanylidene-isoquinolin-2-yl)ethanoyl]piperazine-1-carboxylate | ethyl 4-[2-(3-methyl-1-oxoisoquinolin-2-yl)acetyl]piperazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H23N3O4
Mol. Mass.:
357.4036
SMILES:
CCOC(=O)N1CCN(CC1)C(=O)Cn1c(C)cc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: