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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42162
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42162
Synonyms:
2-[(4-morpholin-4-ylsulfonylbenzoyl)amino]-2-phenylacetic acid | 2-[(4-morpholin-4-ylsulfonylphenyl)carbonylamino]-2-phenyl-ethanoic acid | 2-[(4-morpholinosulfonylbenzoyl)amino]-2-phenyl-acetic acid | 2-[[[4-(4-morpholinylsulfonyl)phenyl]-oxomethyl]amino]-2-phenylacetic acid | MLS000089141 | SMR000072837 | cid_2771104 | {[4-(4-morpholinylsulfonyl)benzoyl]amino}(phenyl)acetic acid
Type:
Small organic molecule
Emp. Form.:
C19H20N2O6S
Mol. Mass.:
404.437
SMILES:
OC(=O)C(NC(=O)c1ccc(cc1)S(=O)(=O)N1CCOCC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: