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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42163
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42163
Synonyms:
2-[[5-(2-methoxy-2-oxidanylidene-ethyl)-1,3-thiazol-2-yl]carbamoyl]bicyclo[2.2.1]heptane-3-carboxylic acid | 2-[[5-(2-methoxy-2-oxoethyl)-1,3-thiazol-2-yl]carbamoyl]bicyclo[2.2.1]heptane-3-carboxylic acid | 2-[[[5-(2-methoxy-2-oxoethyl)-2-thiazolyl]amino]-oxomethyl]-3-bicyclo[2.2.1]heptanecarboxylic acid | 3-({[5-(2-methoxy-2-oxoethyl)-1,3-thiazol-2-yl]amino}carbonyl)bicyclo[2.2.1]heptane-2-carboxylic acid | 3-[[5-(2-keto-2-methoxy-ethyl)thiazol-2-yl]carbamoyl]norbornane-2-carboxylic acid | MLS000088341 | SMR000071699 | cid_2930992
Type:
Small organic molecule
Emp. Form.:
C15H18N2O5S
Mol. Mass.:
338.379
SMILES:
[H]C12CCC([H])(C1)C(C2C(O)=O)C(=O)Nc1ncc(CC(=O)OC)s1 |TLB:12:7:6:3.2,THB:9:8:6:3.2|
Structure:
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