Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM42069
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
7181±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM42069
Synonyms:
2-acetamido-4,5-dinitro-benzoic acid ethyl ester | 2-acetamido-4,5-dinitrobenzoic acid ethyl ester | MLS000698400 | SMR000224624 | cid_4104905 | ethyl 2-(acetylamino)-4,5-dinitrobenzoate | ethyl 2-acetamido-4,5-dinitro-benzoate | ethyl 2-acetamido-4,5-dinitrobenzoate
Type:
Small organic molecule
Emp. Form.:
C11H11N3O7
Mol. Mass.:
297.2209
SMILES:
CCOC(=O)c1cc(c(cc1NC(C)=O)[N+]([O-])=O)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: