Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43529
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43529
Synonyms:
2-(4-methylphenyl)-5-pyridin-4-yl-4H-benzo[i][1,3,4]benzotriazepine | 2-(p-tolyl)-5-(4-pyridyl)-4H-benzo[i][1,3,4]benzotriazepine | MLS000688074 | SMR000284259 | cid_3166385
Type:
Small organic molecule
Emp. Form.:
C24H18N4
Mol. Mass.:
362.4265
SMILES:
Cc1ccc(cc1)C1=NNC(c2ccncc2)=c2ccc3ccccc3c2=N1 |c:30,t:8,18|
Structure:
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