Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43530
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43530
Synonyms:
1-[(3,4-dimethoxyphenyl)methyl]-4-thiophen-2-yl-4H-pyridine-3,5-dicarboxylic acid dimethyl ester | 4-(2-thienyl)-1-veratryl-4H-pyridine-3,5-dicarboxylic acid dimethyl ester | MLS000718851 | SMR000291119 | cid_1272579 | dimethyl 1-[(3,4-dimethoxyphenyl)methyl]-4-thiophen-2-yl-4H-pyridine-3,5-dicarboxylate
Type:
Small organic molecule
Emp. Form.:
C22H23NO6S
Mol. Mass.:
429.486
SMILES:
COC(=O)C1=CN(Cc2ccc(OC)c(OC)c2)C=C(C1c1cccs1)C(=O)OC |c:19,t:4|
Structure:
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