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Target
Procathepsin L
Ligand
BDBM41164
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response testing in the presence of cysteine
IC50
3763.483333±947.717525 nM
Citation
 PubChem, PC Cathepsin L dose-response testing in the presence of cysteine PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41164
Synonyms:
MLS000047299 | N-[1-(2-furyl)-3-indolin-1-yl-3-keto-propyl]-4-methoxy-benzenesulfonamide | N-[3-(2,3-dihydro-1H-indol-1-yl)-1-(2-furyl)-3-oxopropyl]-4-methoxybenzenesulfonamide | N-[3-(2,3-dihydroindol-1-yl)-1-(2-furanyl)-3-oxopropyl]-4-methoxybenzenesulfonamide | N-[3-(2,3-dihydroindol-1-yl)-1-(furan-2-yl)-3-oxidanylidene-propyl]-4-methoxy-benzenesulfonamide | N-[3-(2,3-dihydroindol-1-yl)-1-(furan-2-yl)-3-oxopropyl]-4-methoxybenzenesulfonamide | SMR000033310 | cid_3243146
Type:
Small organic molecule
Emp. Form.:
C22H22N2O5S
Mol. Mass.:
426.485
SMILES:
COc1ccc(cc1)S(=O)(=O)NC(CC(=O)N1CCc2ccccc12)c1ccco1
Structure:
Search PDB for entries with ligand similarity: