Reaction Details Report a problem with these data
Target
Phosphomannomutase 2
Ligand
BDBM46720
Substrate
n/a
Meas. Tech.
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
IC50
4800±n/a nM
Citation
 PubChem, PC Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay PubChem Bioassay (2010)[AID] 
Target
Name:
Phosphomannomutase 2
Synonyms:
PMM2 | PMM2_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28082.33
Organism:
Homo sapiens (Human)
Description:
gi_4557839
Residue:
246
Sequence:
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
  
Inhibitor
Name:
BDBM46720
Synonyms:
(3-bromo-2-nitro-phenyl)-(4-chlorodithiazol-5-ylidene)amine | MLS-0390932.0001 | N-(3-bromanyl-2-nitro-phenyl)-4-chloranyl-1,2,3-dithiazol-5-imine | N-(3-bromo-2-nitrophenyl)-4-chloro-5-dithiazolimine | N-(3-bromo-2-nitrophenyl)-4-chlorodithiazol-5-imine | cid_25181240
Type:
Small organic molecule
Emp. Form.:
C8H3BrClN3O2S2
Mol. Mass.:
352.615
SMILES:
[O-][N+](=O)c1c(Br)cccc1\N=c1\ssnc1Cl
Structure:
Search PDB for entries with ligand similarity: