Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM30734
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.00913±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM30734
Synonyms:
6-chloranyl-2-(4-methylpiperazin-1-yl)-4-phenyl-quinazoline | 6-chloro-2-(4-methyl-1-piperazinyl)-4-phenylquinazoline | 6-chloro-2-(4-methylpiperazin-1-yl)-4-phenylquinazoline | 6-chloro-2-(4-methylpiperazino)-4-phenyl-quinazoline | MLS000068813 | SMR000034326 | cid_659436
Type:
Small organic molecule
Emp. Form.:
C19H19ClN4
Mol. Mass.:
338.834
SMILES:
CN1CCN(CC1)c1nc(-c2ccccc2)c2cc(Cl)ccc2n1
Structure:
Search PDB for entries with ligand similarity: