Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM48921
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.114±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM48921
Synonyms:
4-butoxy-6-methyl-N-(phenylmethyl)-2-pyrimidinamine | 4-butoxy-6-methyl-N-(phenylmethyl)pyrimidin-2-amine | MLS000078574 | N-benzyl-4-butoxy-6-methylpyrimidin-2-amine | SMR000040993 | benzyl-(4-butoxy-6-methyl-pyrimidin-2-yl)amine | cid_659995
Type:
Small organic molecule
Emp. Form.:
C16H21N3O
Mol. Mass.:
271.3574
SMILES:
CCCCOc1cc(C)nc(NCc2ccccc2)n1
Structure:
Search PDB for entries with ligand similarity: