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Target
D(1A) dopamine receptor
Ligand
BDBM49005
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.123±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49005
Synonyms:
3-amino-5-phenyl-2-propyl-4-thieno[2,3-d]pyrimidinone | 3-amino-5-phenyl-2-propyl-thieno[2,3-d]pyrimidin-4-one | 3-amino-5-phenyl-2-propylthieno[2,3-d]pyrimidin-4-one | 3-azanyl-5-phenyl-2-propyl-thieno[2,3-d]pyrimidin-4-one | MLS000036186 | SMR000036040 | cid_660486
Type:
Small organic molecule
Emp. Form.:
C15H15N3OS
Mol. Mass.:
285.364
SMILES:
CCCc1nc2scc(-c3ccccc3)c2c(=O)n1N
Structure:
Search PDB for entries with ligand similarity: