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Target
Induced myeloid leukemia cell differentiation protein Mcl-1
Ligand
BDBM50523
Substrate
n/a
Meas. Tech.
Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors
IC50
3359.599945±n/a nM
Citation
 PubChem, PC Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors PubChem Bioassay (2008)[AID] 
Target
Name:
Induced myeloid leukemia cell differentiation protein Mcl-1
Synonyms:
BCL2L3 | Bcl-2-like protein 3 | Bcl-2-like protein 3 (Mcl-1) | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | Induced myeloid leukemia cell differentiation protein (Mcl-1) | MCL1 | MCL1_HUMAN | Mcl-1 | Myeloid Cell factor-1 (Mcl-1) | Myeloid cell leukemia sequence 1 (BCL2-related) | mcl1/EAT
Type:
Membrane; Single-pass membrane protein
Mol. Mass.:
37332.87
Organism:
Homo sapiens (Human)
Description:
Q07820
Residue:
350
Sequence:
MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
  
Inhibitor
Name:
BDBM50523
Synonyms:
(5Z)-5-[4-(2,4-dinitrophenoxy)-3-methoxy-benzylidene]thiazolidine-2,4-quinone | (5Z)-5-[4-(2,4-dinitrophenoxy)-3-methoxybenzylidene]-1,3-thiazolidine-2,4-dione | (5Z)-5-[[4-(2,4-dinitrophenoxy)-3-methoxy-phenyl]methylidene]-1,3-thiazolidine-2,4-dione | (5Z)-5-[[4-(2,4-dinitrophenoxy)-3-methoxyphenyl]methylidene]-1,3-thiazolidine-2,4-dione | (5Z)-5-[[4-(2,4-dinitrophenoxy)-3-methoxyphenyl]methylidene]thiazolidine-2,4-dione | MLS000722963 | SMR000304958 | cid_5885533
Type:
Small organic molecule
Emp. Form.:
C17H11N3O8S
Mol. Mass.:
417.35
SMILES:
COc1cc(\C=C2/SC(=O)NC2=O)ccc1Oc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O
Structure:
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