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Target
Zinc finger protein mex-5
Ligand
BDBM52492
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52492
Synonyms:
(E)-1-(2,4-dimethoxyphenyl)-3-(3-nitro-4-piperidin-1-yl-phenyl)prop-2-en-1-one | (E)-1-(2,4-dimethoxyphenyl)-3-(3-nitro-4-piperidin-1-ylphenyl)prop-2-en-1-one | (E)-1-(2,4-dimethoxyphenyl)-3-(3-nitro-4-piperidino-phenyl)prop-2-en-1-one | (E)-1-(2,4-dimethoxyphenyl)-3-[3-nitro-4-(1-piperidinyl)phenyl]-2-propen-1-one | MLS000390406 | SMR000255373 | cid_15945163
Type:
Small organic molecule
Emp. Form.:
C22H24N2O5
Mol. Mass.:
396.4364
SMILES:
COc1ccc(C(=O)\C=C\c2ccc(N3CCCCC3)c(c2)[N+]([O-])=O)c(OC)c1
Structure:
Search PDB for entries with ligand similarity: