Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52860
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52860
Synonyms:
2-chloranyl-5-[2-[(1Z)-1-pyrrol-2-ylideneethyl]hydrazinyl]benzoic acid | 2-chloro-5-[2-[(1Z)-1-pyrrol-2-ylideneethyl]hydrazinyl]benzoic acid | 2-chloro-5-[N'-[(1Z)-1-pyrrol-2-ylideneethyl]hydrazino]benzoic acid | 2-chloro-5-[[(1Z)-1-(2-pyrrolylidene)ethyl]hydrazo]benzoic acid | MLS000776192 | SMR000371191 | cid_16682669
Type:
Small organic molecule
Emp. Form.:
C13H12ClN3O2
Mol. Mass.:
277.706
SMILES:
CC(N=Nc1ccc(Cl)c(c1)C(O)=O)c1ccc[nH]1 |w:3.3|
Structure:
Search PDB for entries with ligand similarity: