Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52866
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52866
Synonyms:
(5Z)-1-methyl-5-(1H-pyrrol-2-ylmethylene)barbituric acid | (5Z)-1-methyl-5-(1H-pyrrol-2-ylmethylidene)-1,3-diazinane-2,4,6-trione | 1-Methyl-5-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-pyrimidine-2,4,6-trione | MLS000779328 | SMR000416042 | cid_5414752
Type:
Small organic molecule
Emp. Form.:
C10H9N3O3
Mol. Mass.:
219.1968
SMILES:
CN1C(=O)NC(=O)\C(=C\c2ccc[nH]2)C1=O
Structure:
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