Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM51290
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
40554±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM51290
Synonyms:
3-Amino-6-pyridin-3-yl-thieno[2,3-b]pyridine-2-carboxylic acid (4-methoxy-phenyl)-amide | 3-amino-N-(4-methoxyphenyl)-6-(3-pyridinyl)-2-thieno[2,3-b]pyridinecarboxamide | 3-amino-N-(4-methoxyphenyl)-6-(3-pyridyl)thieno[2,3-b]pyridine-2-carboxamide | 3-amino-N-(4-methoxyphenyl)-6-pyridin-3-ylthieno[2,3-b]pyridine-2-carboxamide | 3-azanyl-N-(4-methoxyphenyl)-6-pyridin-3-yl-thieno[2,3-b]pyridine-2-carboxamide | MLS000333163 | SMR000436608 | cid_3518029
Type:
Small organic molecule
Emp. Form.:
C20H16N4O2S
Mol. Mass.:
376.432
SMILES:
COc1ccc(NC(=O)c2sc3nc(ccc3c2N)-c2cccnc2)cc1
Structure:
Search PDB for entries with ligand similarity: