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Target
POsterior Segregation
Ligand
BDBM52889
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
30853±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52889
Synonyms:
4-(7-hydrocinnamoyloxy-6,8-diketo-7-methyl-isochromen-3-yl)butyric acid methyl ester | 4-[7-methyl-6,8-dioxo-7-(1-oxo-3-phenylpropoxy)-2-benzopyran-3-yl]butanoic acid methyl ester | CMLD004864 | MLS000438876 | SMR000452596 | cid_16745663 | methyl 4-[7-methyl-6,8-bis(oxidanylidene)-7-(3-phenylpropanoyloxy)isochromen-3-yl]butanoate | methyl 4-[7-methyl-6,8-dioxo-7-(3-phenylpropanoyloxy)isochromen-3-yl]butanoate
Type:
Small organic molecule
Emp. Form.:
C24H24O7
Mol. Mass.:
424.4432
SMILES:
COC(=O)CCCC1=CC2=CC(=O)C(C)(OC(=O)CCc3ccccc3)C(=O)C2=CO1 |c:30,t:7,9|
Structure:
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