Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52893
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
95706±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52893
Synonyms:
4-methoxybenzoic acid [3-butyl-5-(2-furanyl)-7-methyl-2-[2-(4-morpholinyl)ethyl]-6,8-dioxo-7-isoquinolinyl] ester | 4-methoxybenzoic acid [3-butyl-5-(2-furyl)-6,8-diketo-7-methyl-2-(2-morpholinoethyl)-7-isoquinolyl] ester | CMLD004043 | MLS001045901 | SMR000452796 | [3-butyl-5-(furan-2-yl)-7-methyl-2-(2-morpholin-4-ylethyl)-6,8-bis(oxidanylidene)isoquinolin-7-yl] 4-methoxybenzoate | [3-butyl-5-(furan-2-yl)-7-methyl-2-(2-morpholin-4-ylethyl)-6,8-dioxoisoquinolin-7-yl] 4-methoxybenzoate | cid_16745675
Type:
Small organic molecule
Emp. Form.:
C32H36N2O7
Mol. Mass.:
560.6374
SMILES:
CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1CCN1CCOCC1 |c:6,33,t:4|
Structure:
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