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Target
Procathepsin L
Ligand
BDBM55156
Substrate
n/a
Meas. Tech.
QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1).
IC50
>59642±n/a nM
Citation
 PubChem, PC QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Human
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM55156
Synonyms:
MLS001174685 | N-[2-(3,4-dihydroxyphenyl)ethyl]-2,3-dihydro-1,4-benzodioxin-3-carboxamide | N-[2-(3,4-dihydroxyphenyl)ethyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide | N-[2-[3,4-bis(oxidanyl)phenyl]ethyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide | SMR000589646 | cid_4657144
Type:
Small organic molecule
Emp. Form.:
C17H17NO5
Mol. Mass.:
315.3206
SMILES:
Oc1ccc(CCNC(=O)C2COc3ccccc3O2)cc1O
Structure:
Search PDB for entries with ligand similarity: