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Target
Kallikrein-5
Ligand
BDBM56535
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
26487.14±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM56535
Synonyms:
2-furancarboxylic acid [2-methoxy-4-[(Z)-[1-(3-methylphenyl)-3,5-dioxo-4-pyrazolidinylidene]methyl]phenyl] ester | 2-methoxy-4-{[1-(3-methylphenyl)-3,5-dioxo-4-pyrazolidinylidene]methyl}phenyl 2-furoate | MLS000577943 | SMR000198345 | [2-methoxy-4-[(Z)-[1-(3-methylphenyl)-3,5-bis(oxidanylidene)pyrazolidin-4-ylidene]methyl]phenyl] furan-2-carboxylate | [2-methoxy-4-[(Z)-[1-(3-methylphenyl)-3,5-dioxopyrazolidin-4-ylidene]methyl]phenyl] furan-2-carboxylate | cid_2189210 | furan-2-carboxylic acid [4-[(Z)-[3,5-diketo-1-(m-tolyl)pyrazolidin-4-ylidene]methyl]-2-methoxy-phenyl] ester
Type:
Small organic molecule
Emp. Form.:
C23H18N2O6
Mol. Mass.:
418.3988
SMILES:
COc1cc(\C=C2\C(=O)NN(C2=O)c2cccc(C)c2)ccc1OC(=O)c1ccco1
Structure:
Search PDB for entries with ligand similarity: