Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM51788
Substrate
n/a
Meas. Tech.
uHTS absorbance assay for the identification of compounds that inhibit VHR1.
IC50
2280±n/a nM
Citation
 PubChem, PC uHTS absorbance assay for the identification of compounds that inhibit VHR1. PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM51788
Synonyms:
5-[(2E)-2-(8-oxidanylidenequinolin-5-ylidene)hydrazinyl]naphthalene-1-sulfonic acid | 5-[(2E)-2-(8-oxo-5-quinolinylidene)hydrazinyl]-1-naphthalenesulfonic acid | 5-[(2E)-2-(8-oxoquinolin-5-ylidene)hydrazinyl]naphthalene-1-sulfonic acid | 5-[(E)-(8-hydroxyquinolin-5-yl)diazenyl]naphthalene-1-sulfonic acid | 5-[(N'E)-N'-(8-keto-5-quinolylidene)hydrazino]naphthalene-1-sulfonic acid | MLS001197249 | SMR000555383 | cid_5876309
Type:
Small organic molecule
Emp. Form.:
C19H13N3O4S
Mol. Mass.:
379.389
SMILES:
Oc1ccc(N=Nc2cccc3c(cccc23)S(O)(=O)=O)c2cccnc12 |w:6.6|
Structure:
Search PDB for entries with ligand similarity: