Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM37551
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM37551
Synonyms:
MLS000082016 | N-[2-(4-methoxyphenyl)ethyl]-2,3-dihydro-1,4-dioxin-5-carboxamide | N-[2-(4-methoxyphenyl)ethyl]-2,3-dihydro-1,4-dioxine-5-carboxamide | N-[2-(4-methoxyphenyl)ethyl]-2,3-dihydro-p-dioxin-5-carboxamide | SMR000061349 | cid_2354370
Type:
Small organic molecule
Emp. Form.:
C14H17NO4
Mol. Mass.:
263.2891
SMILES:
COc1ccc(CCNC(=O)C2=COCCO2)cc1 |t:11|
Structure:
Search PDB for entries with ligand similarity: