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Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM39089
Substrate
n/a
Meas. Tech.
Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress
IC50
350±n/a nM
Citation
 PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay (2010)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM39089
Synonyms:
2-(5-bromanyl-2-chloranyl-phenyl)-1,3-benzoxazol-5-amine | 2-(5-bromo-2-chlorophenyl)-1,3-benzoxazol-5-amine | MLS000036810 | SMR000036737 | [2-(5-bromo-2-chloro-phenyl)-1,3-benzoxazol-5-yl]amine | cid_659499
Type:
Small organic molecule
Emp. Form.:
C13H8BrClN2O
Mol. Mass.:
323.572
SMILES:
Nc1ccc2oc(nc2c1)-c1cc(Br)ccc1Cl
Structure:
Search PDB for entries with ligand similarity: