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Target
Intestinal-type alkaline phosphatase
Ligand
BDBM75762
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Intestinal-type alkaline phosphatase
Synonyms:
ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN
Type:
PROTEIN
Mol. Mass.:
56804.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1278525
Residue:
528
Sequence:
MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
  
Inhibitor
Name:
BDBM75762
Synonyms:
3,4,5-trimethoxy-N-[2-[2-[[5-(4-nitrophenyl)-2-furanyl]methylidene]hydrazinyl]-2-oxoethyl]benzamide | 3,4,5-trimethoxy-N-[2-[2-[[5-(4-nitrophenyl)furan-2-yl]methylidene]hydrazinyl]-2-oxidanylidene-ethyl]benzamide | 3,4,5-trimethoxy-N-[2-[2-[[5-(4-nitrophenyl)furan-2-yl]methylidene]hydrazinyl]-2-oxoethyl]benzamide | MLS000912522 | N-[2-keto-2-[N'-[[5-(4-nitrophenyl)-2-furyl]methylene]hydrazino]ethyl]-3,4,5-trimethoxy-benzamide | SMR000620552 | cid_3636488
Type:
Small organic molecule
Emp. Form.:
C23H22N4O8
Mol. Mass.:
482.4428
SMILES:
COc1cc(cc(OC)c1OC)C(=O)NCC(=O)N\N=C\c1ccc(o1)-c1ccc(cc1)[N+]([O-])=O
Structure:
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