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Target
Neurotensin receptor type 1
Ligand
BDBM79526
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
6240±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79526
Synonyms:
(3Z)-3-[2-(5-bromanylthiophen-2-yl)-2-oxidanylidene-ethylidene]-5,7-dimethyl-1H-indol-2-one | (3Z)-3-[2-(5-bromo-2-thienyl)-2-keto-ethylidene]-5,7-dimethyl-oxindole | (3Z)-3-[2-(5-bromo-2-thiophenyl)-2-oxoethylidene]-5,7-dimethyl-1H-indol-2-one | (3Z)-3-[2-(5-bromothiophen-2-yl)-2-oxoethylidene]-5,7-dimethyl-1H-indol-2-one | 3-[2-(5-bromo-2-thienyl)-2-oxoethylidene]-5,7-dimethyl-1,3-dihydro-2H-indol-2-one | MLS000594195 | SMR000143214 | cid_2199612
Type:
Small organic molecule
Emp. Form.:
C16H12BrNO2S
Mol. Mass.:
362.241
SMILES:
Cc1cc2\C(=C\C(=O)c3ccc(Br)s3)C(=O)Nc2c(C)c1
Structure:
Search PDB for entries with ligand similarity: