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Target
Neurotensin receptor type 1
Ligand
BDBM39784
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
13000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM39784
Synonyms:
(5E)-1-(3-methylphenyl)-5-[(1-phenyl-4-pyrazolyl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-1-(3-methylphenyl)-5-[(1-phenylpyrazol-4-yl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-1-(m-tolyl)-5-[(1-phenylpyrazol-4-yl)methylene]barbituric acid | 1-(3-methylphenyl)-5-[(1-phenyl-1H-pyrazol-4-yl)methylene]-2,4,6(1H,3H,5H)-pyrimidinetrione | MLS000573946 | SMR000195533 | cid_2198843
Type:
Small organic molecule
Emp. Form.:
C21H16N4O3
Mol. Mass.:
372.3767
SMILES:
Cc1cccc(c1)N1C(=O)NC(=O)C(=Cc2cnn(c2)-c2ccccc2)C1=O |w:14.15|
Structure:
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