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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM33184
Substrate
n/a
Meas. Tech.
Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase
IC50
30200±n/a nM
Citation
 PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay (2011)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b
Type:
Enzyme
Mol. Mass.:
59258.58
Organism:
Homo sapiens (Human)
Description:
P11413
Residue:
515
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
  
Inhibitor
Name:
BDBM33184
Synonyms:
2-[1-oxidanylidene-4-(2,4,5-trimethylphenyl)sulfonylimino-naphthalen-2-yl]sulfanylethanoic acid | 2-[1-oxo-4-(2,4,5-trimethylphenyl)sulfonyliminonaphthalen-2-yl]sulfanylacetic acid | 2-[[1-keto-4-(2,4,5-trimethylphenyl)sulfonylimino-2-naphthyl]thio]acetic acid | 2-[[1-oxo-4-(2,4,5-trimethylphenyl)sulfonylimino-2-naphthalenyl]thio]acetic acid | MLS000689768 | SMR000313372 | [((4Z)-1-oxo-4-{[(2,4,5-trimethylphenyl)sulfonyl]imino}-1,4-dihydronaphthalen-2-yl)thio]acetic acid | cid_3676835
Type:
Small organic molecule
Emp. Form.:
C21H19NO5S2
Mol. Mass.:
429.509
SMILES:
Cc1cc(C)c(cc1C)S(=O)(=O)N=C1C=C(SCC(O)=O)C(=O)c2ccccc12 |w:12.12,t:15|
Structure:
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