Ki Summary

Reaction Details

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Target

Somatostatin receptor type 4

Ligand

BDBM82469

Substrate

n/a

1.81±n/a nM

Comments

PDSP_372

Citation

Hoyer, D; Lübbert, H; Bruns, C Molecular pharmacology of somatostatin receptors. Naunyn Schmiedebergs Arch Pharmacol 350:441-53 (1994) [PubMed] Article

More Info.:

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Target

Name:

Somatostatin receptor type 4

Synonyms:

SS-4-R | SS4-R | SS4R | SSR4_MOUSE | Smstr4 | Sstr4

Type:

PROTEIN

Mol. Mass.:

41937.48

Organism:

Mus musculus

Description:

ChEMBL_833920

Residue:

385

Sequence:

MNAPATLPPGVEDTTWTPGINASWAPDEEEEDAMGSDGTGTAGMVTIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFARSAAALRHWPFGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLATATYRRPSVAKLINLGVWLASLLVTLPIAVFADTRPARGGEAVACNLHWPHPAWSAVFVIYTFLLGFLPPVLAIGLCYLLIVGKMRAVALAGGWQQRRRSEKKITRLVLMVVTVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRSFQRVLCLRCCLLETTGGAEEEPLDYYATALKSRGGAGCICPPLPCQQEPVQAEPGCKQVPFTKTTTF

Inhibitor

Name:

BDBM82469

Synonyms:

BIM 23003 | BIM-23003 | EC5-21 | L-Cys(1)-L-Lys-L-Asn-4-Chloro-L-Phe-L-Phe-D-Trp-L-Lys-L-Thr-L-Phe-L-Thr-L-Ser-L-Cys(1)-OH

Type:

Small organic molecule

Emp. Form.:

C71H95ClN16O17S2

Mol. Mass.:

1544.194

SMILES:

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O

Structure: