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Target
Alpha-2A adrenergic receptor
Ligand
BDBM30993
Substrate
n/a
Ki
10±n/a nM
Comments
PDSP_1589
Citation
 O'Rourke, MF; Iversen, LJ; Lomasney, JW; Bylund, DB Species orthologs of the alpha-2A adrenergic receptor: the pharmacological properties of the bovine and rat receptors differ from the human and porcine receptors. J Pharmacol Exp Ther 271:735-40 (1994) [PubMed] 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
Alpha-2A adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48998.96
Organism:
PIG
Description:
adrenergic Alpha2 0 PIG::P18871
Residue:
450
Sequence:
MGSLQPEAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKAGGGGQQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAAAALPGGAERRPNGLGPERGVGRVGAEAEPLPVQLNGAPGEPAPAGPRDADGLDLEESSSSEHAERPPGPRRSERGPRAKSKARASQVKPGDSLPRRGPGAPGPGAPATGAGEERGGVAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM30993
Synonyms:
Ajmalicine | MLS000111555 | Raubasine | SMR000107477 | cid_251561
Type:
Small organic molecule
Emp. Form.:
C21H24N2O3
Mol. Mass.:
352.4269
SMILES:
COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12 |t:4|
Structure:
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