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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM50266693
Substrate
n/a
Meas. Tech.
ChEMBL_1714761 (CHEMBL4124810)
EC50
0.031000±n/a nM
Citation
 Evers, A; Bossart, M; Pfeiffer-Marek, S; Elvert, R; Schreuder, H; Kurz, M; Stengelin, S; Lorenz, M; Herling, A; Konkar, A; Lukasczyk, U; Pfenninger, A; Lorenz, K; Haack, T; Kadereit, D; Wagner, M Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations. J Med Chem 61:5580-5593 (2018) [PubMed]  Article 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP1R | Glucagon-like peptide 1 receptor
Type:
PROTEIN
Mol. Mass.:
52947.60
Organism:
Macaca fascicularis
Description:
ChEMBL_117790
Residue:
463
Sequence:
MAGTPGPLRLALLLLGVVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERNSPEEQLLSLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRVVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQRIFRLYVSVGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM50266693
Synonyms:
CHEBI:5391 | Glucagen Hypokit | Glucagon | Glucagon Emergency Kit | Glucagon Recombinant
Type:
Small organic molecule
Emp. Form.:
C153H225N43O49S
Mol. Mass.:
3482.747
SMILES:
n/a
Structure:
Search PDB for entries with ligand similarity: