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Target
D(2) dopamine receptor
Ligand
BDBM50026172
Substrate
n/a
Meas. Tech.
ChEBML_58707
IC50
1050±n/a nM
Citation
 Bagli, J; Bogri, T; Voith, K; Lee, D Troponoids. 7. Chemistry and dopamine agonist activity of ciladopa and related aralkyltroponylpiperazines. J Med Chem 29:186-93 (1986) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50026172
Synonyms:
2-{4-[2-(3,4-Dimethoxy-phenyl)-2-hydroxy-1-methyl-ethyl]-piperazin-1-yl}-cyclohepta-2,4,6-trienone | 2-{4-[2-Hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-ethyl]-piperazin-1-yl}-cyclohepta-2,4,6-trienone | CHEMBL57437
Type:
Small organic molecule
Emp. Form.:
C22H28N2O4
Mol. Mass.:
384.4687
SMILES:
COc1ccc(cc1OC)[C@H](O)[C@@H](C)N1CCN(CC1)c1cccccc1=O
Structure:
Search PDB for entries with ligand similarity: